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28. PATHOPHYSIOLOGY OF ALCOHOLISM AND DRUG ADDICTION. NEUROSIS

I. Alcohol intoxication is accompanied by the following metabolic disturbances:

1. Inhibition of gluconeogenesis in the liver.

2. Inhibition of protein synthesis.

3. Stimulation of lipolysis in the adipose tissue.

4. Increased production of ketone bodies by the liver.

5. Inhibition of glycogenolysis.

6. Decreased production of high density lipoproteins.

7. Stimulation of glycogenesis.

II. Alcohol withdrawal syndrome may be manifested by the following:

1. Tremor.

2. Depressive mood, irritability.

3. Seizures.

4. Tachycardia.

5. Sleeplessness.

6. Bradycardia.

7. Dry skin.

III. Severe intoxication by sedative and soporific drugs is manifested by the following:

1. Hypotension.

2. Mydriasis.

3. Ataxia.

4. Vertical and horizontal nystagmus.

5. Myosis.

6. Hyperthermia.

7. Fussiness and excitement.

IV. Intoxication by psychostimulants is manifested by the following:

1. Hypertension.

2. Tachypnea.

3. Tachycardia.

4. Excitement and restlessness.

5. Stereotypy.

6. Mydriasis.

7. Ataxia.

8. Hypothermia.

V. The laboratory tests that are likely to be abnormal in the alcoholic patient include:

1. Mean cellular volume of the red blood cells.

2. Activity of plasma gamma-glutamyltransferase.

3. Serum uric acid.

4. Serum level of carbohydrate-deficient transferrin.

5. Triglycerides.

6. Cholesterol.

7. Glucose.

8. Ketone bodies.

VI. The most common complications of alcohol abuse are:

1. Chronic hepatitis and cirrhosis.

2. Cardiomyopathy.

3. Chronic pancreatitis.

4. Peripheral neuropathy.

5. Wernicke's syndrome.

6. Atherosclerosis.

7. Hypotension.

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