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12. TYPICAL DISORDERS OF THE HOST DEFENCE SYSTEM

I. T-cells participate directly in the following processes:

1. Direct cytolysis.

2. Promotion of B-cell activities.

3. Supression of T-cell activities.

4. Antigen presentation.

5. Lymphokine production.

6. Production of complement.

7. Production of antibodies.

II. Which of the following immunodeficiency disorders are the most common?

1. Bruton's agammaglobulinemia.

2. DiGeorge's syndrome.

3. Selective IgA deficiency.

4. Common variable immunodeficiency.

5. Severe combined immunodeficiency.

III. The target for human immunodeficiency virus (HIV) are:

1. T-cells.

2. Natural killer cells.

3. Dendritic cells.

4. B-cells.

5. Eosinophils.

6. Monocytes.

7. Tissue macrophages.

8. Platelets.

IV. Human immunodeficiency virus can bind with the following superficial cell receptors:

1. CD8+.

2. CD3.

3. CD4+.

4. Fc.

5. CD21.

V. Clinical and immunologic features of DiGeorge syndrome include:

1. Hypercalcemia.

2. Tetany.

3. The absence or decreased size of the thymus.

4. The absence of plasma cells.

5. Low levels of circulating T-cells.

6. A poor defence against fungal infections.

7. A poor defence against viral infections.

8. Recurrent pyogenic infections.

VI. Immunodeficiency states associated with nonspecific defence reactions may be caused by disorders of the following processes:

1. Synthesis of antibodies.

2. Phagocytosis mediated by mononuclear phagocytes.

3. Phagocytosis mediated by neutrophils.

4. Production of T-cells.

5. Production of oxygen free radicals.

6. Production of the complement components.

7. Secretion of lytic granules by T-cells.

VII. Which of the following organs and tissues can be the target of autoimmune aggression induced by a breakdown of the histo-hematic barrier?

1. Thyroid gland.

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